{"id":212,"date":"2020-05-15T03:19:28","date_gmt":"2020-05-15T00:19:28","guid":{"rendered":"https:\/\/blog.drozberk.com\/?p=212"},"modified":"2020-07-03T17:33:35","modified_gmt":"2020-07-03T14:33:35","slug":"cadi-findigihamamelis-virginiana","status":"publish","type":"post","link":"http:\/\/blog.drozberk.com\/index.php\/2020\/05\/15\/cadi-findigihamamelis-virginiana\/","title":{"rendered":"CADI FINDI\u011eI(HAMAMEL\u0130S V\u0130RG\u0130N\u0130ANA)"},"content":{"rendered":"\n

A\u015fa\u011f\u0131da cad\u0131 f\u0131nd\u0131\u011f\u0131 bitkisi ile ilgili literat\u00fcre kay\u0131tl\u0131 \u00e7al\u0131\u015fmalar\u0131n \u00f6zeti yer almaktad\u0131r. Bu \u00e7al\u0131\u015fmalar\u0131n tamam\u0131n\u0131 okumak i\u00e7in DOI numalar\u0131ndan ula\u015fabilirsiniz.<\/strong><\/p>\n\n\n\n

MAKALE 1-)https:\/\/scihub.bban.top\/10.4103\/0974-7753.139079<\/a> <\/p>\n\n\n\n

North American Virginian Witch Hazel (Hamamelis\nVirginiana): Based Scalp Care and Protection for Sensitive Scalp, Red Scalp,\nand Scalp Burn-Out<\/h1>\n\n\n\n

Ama\u00e7: <\/strong>Hassas bir kafa\nderisi g\u00fcnl\u00fck klinik uygulamada s\u0131k g\u00f6r\u00fclen bir sorundur ve genellikle\ndermatologlar i\u00e7in b\u00fcy\u00fck bir zorluktur.<\/h1>\n\n\n\n

Ama\u00e7: <\/strong>Northamerican Virginian Cad\u0131 Hazel (Hamamelis virginiana) bazl\u0131\n\u015fampuan ve tonik (Erol (\u00ae) Enerjisinin) hassas kafa derisinin tedavisi i\u00e7in\netkinli\u011fini de\u011ferlendirmekti.<\/p>\n\n\n\n

Y\u00f6ntemler: <\/strong>Erol\u00ae \u00ae Enerji \u00fcr\u00fcnleri Dermatoloji ve Sa\u00e7 Hastal\u0131klar\u0131 Merkezi\nProfes\u00f6r\u00fc Tr\u00fceb’de A\u011fustos 2010 ve Aral\u0131k 2013 tarihleri \u200b\u200baras\u0131nda irrotabl\nkafa derisi rahats\u0131zl\u0131klar\u0131n\u0131 tedavi etmek ya da androjenetik tedavisi i\u00e7in\nminoksidil tedavisine e\u015flik eden tedavi edilen erkek ve kad\u0131n hastalar\u0131n\nretrospektif g\u00f6zlemsel \u00e7al\u0131\u015fmas\u0131 alocepia.<\/p>\n\n\n\n

Bulgular: <\/strong>1.373 hastaya (1.233 kad\u0131n ve 140 erkek) \u015fampuan ba\u015far\u0131yla\nuyguland\u0131. Hastalar subjektif tahri\u015f belirtilerinin iyile\u015fti\u011fini ve her\niki \u00fcr\u00fcn\u00fcn de tolerans\u0131n\u0131n iyi ila m\u00fckemmel oldu\u011funu bildirdiler. Bu s\u00fcre\nzarf\u0131nda 369 (% 26.9) bir kereden fazla Erol\u00ae \u015fampuan\u0131 alm\u0131\u015ft\u0131r.<\/p>\n\n\n\n

Sonu\u00e7lar: <\/strong>Uygun sa\u00e7 bak\u0131m \u00fcr\u00fcnlerinin se\u00e7imi, hassas kafa derisi ve ilgili\ndurumlar\u0131n y\u00f6netiminde \u00f6nemli bir y\u00f6n\u00fc temsil etmektedir. Erol (\u00ae) Enerji\nsa\u00e7 bak\u0131m \u00fcr\u00fcnleri ile, \u00f6zellikle k\u0131rm\u0131z\u0131 kafa derisi, kafa derisi yanmas\u0131 ve\ntopikal minoksidil kullan\u0131m\u0131 ile ilgili sorunlar ba\u011flam\u0131nda, H. virginiana’n\u0131n\nkafa derisinin ba\u015far\u0131l\u0131 tedavisi i\u00e7in avantajlar\u0131 mevcuttur.<\/p>\n\n\n\n

MAKALE 2-)    PMID: <\/strong>30052192<\/strong><\/p>\n\n\n\n

Understanding Solar Skin Elastosis-Cause and\nTreatment<\/h1>\n\n\n\n

Aktinik ya\u015flanma olarak da\nadland\u0131r\u0131lan foto ya\u015flanma, erken ya\u015flanm\u0131\u015f cildin ana nedenidir. Elastik\nliflerdeki uzmanl\u0131\u011f\u0131m\u0131z bizi ultraviyole (UV) \u0131\u015f\u0131\u011fa tepki olarak tetiklenen ve\nelastin liflerinin dengesini bozan bir s\u00fcre\u00e7 ke\u015ffetmemize yol a\u00e7t\u0131: fonksiyonel\nelastik lifler olu\u015fturmak i\u00e7in \u00e7ok fazla elastin ve yetersiz lizil oksidaz\n(LOXL1) enzimi var. Bu dengesizlik daha sonra agregat olu\u015fturan\nfonksiyonel olmayan elastin birikmesine yol a\u00e7ar. Bu dengesizli\u011fe ek\nolarak, UV \u0131\u015f\u0131nlar\u0131 fibroblastlar taraf\u0131ndan elafin sentezini de\nind\u00fckler. Elastotik agregalar\u0131n bir belirteci oldu\u011fu bilinen elafin,\nelastin liflerini kristalize eder ve cilt taraf\u0131ndan do\u011fal olarak elimine\nedilemeyen agregalar\u0131n olu\u015fumunu uyar\u0131r. Bir Hamamelis virginiana<\/em> geli\u015ftirdikelastin\nve LOXL1 aras\u0131ndaki dengeyi eski haline getirebilen ve hasar\u0131 gidermek ve\nd\u00fczeltmek i\u00e7in elafin sentezini azaltabilen yaprak \u00f6z\u00fct\u00fc. Bu\nspesifik Hamamelis virginiana<\/em> \u00f6z\u00fct\u00fc, LOXL1 ekspresyonunu iki\nkat artt\u0131rd\u0131 ve elafin sentezini azaltt\u0131. Sonu\u00e7 olarak, elastik lifler i\u015flevsel\nhale geldi ve fonksiyonel olmayan liflerin agregatlar\u0131 azald\u0131. Spesifik\nHamamelis \u00f6z\u00fc aktivitesi, k\u0131r\u0131\u015f\u0131kl\u0131klar\u0131n azalt\u0131lmas\u0131 ve cilt s\u0131k\u0131l\u0131\u011f\u0131n\u0131n\nartt\u0131r\u0131lmas\u0131 ile in vivo<\/em> olarak do\u011fruland\u0131 .<\/p>\n\n\n\n

MAKALE 3-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1007\/s00431-006-0363-1<\/a><\/p>\n\n\n\n

Hamamelis in Children With Skin Disorders and Skin\nInjuries: Results of an Observational Study<\/h1>\n\n\n\n

\u00c7ocuklarda hamamelis merhemiyle\nyay\u0131nlanan klinik deneyim s\u0131n\u0131rl\u0131d\u0131r. Bu g\u00f6zlemsel \u00e7al\u0131\u015fma, k\u00fc\u00e7\u00fck cilt\nyaralanmalar\u0131, bebek bezi dermatiti veya lokal cilt iltihab\u0131 olan \u00e7ocuklar\u0131 (27\ng\u00fcn ila 11 ya\u015f aras\u0131) kapsamaktad\u0131r. \u00c7ocuklara 3’e 1 oran\u0131nda hamamelis\nmerhem veya dekspantenol merhem verildi. Ba\u015flang\u0131\u00e7 \u200b\u200bve tedavi sonras\u0131\nde\u011ferlendirmeler, her bir durum i\u00e7in \u00f6nceden tan\u0131mlanm\u0131\u015f belirti ve\nsemptomlar\u0131n toplam skorlar\u0131n\u0131 kar\u015f\u0131la\u015ft\u0131rd\u0131. Doktorlar ve ebeveynlerden,\ntedavi sonunda ilgili tedavilerin etkinli\u011fi ve tolere edilebilirli\u011finin k\u00fcresel\nbir de\u011ferlendirmesi istendi. Toplam 309 \u00e7ocuk tedavi edildi (hamamelis n =\n231; dekspantenol n = 78). Tedavi gruplar\u0131 demografik veriler ve belirti\nve semptomlar\u0131n ba\u015flang\u0131\u00e7 \u200b\u200btoplam skorlar\u0131 a\u00e7\u0131s\u0131ndan\nkar\u015f\u0131la\u015ft\u0131r\u0131labilirdi. Her \u00fc\u00e7 tan\u0131 grubunda da, hamamelis ve\ndekspantenol\u00fcn etkinli\u011fi, taban \u00e7izgisinden son noktaya kadar istatistiksel\nolarak anlaml\u0131 ve klinik olarak anlaml\u0131 bir d\u00fc\u015f\u00fc\u015fle g\u00f6sterilmi\u015ftir (her grup\ni\u00e7in p <0.0001, Wilcoxon i\u015faretli s\u0131ra testi). Genel olarak, hamamelis\nve dekspantenol gruplar\u0131n\u0131n sonu\u00e7lar\u0131 benzerdi. Bir dizi parametre ve tan\u0131\ngrubunda hamamelis grubu i\u00e7in tan\u0131mlay\u0131c\u0131 avantajlar g\u00f6zlenmi\u015ftir. Her iki\ntedavi de iyi tolere edildi. Hamamelisin tolere edilebilirli\u011fi, s\u0131ras\u0131yla%\n99.1 (doktor) ve% 98.2 (ebeveyn) vakalar\u0131nda “m\u00fckemmel” veya\n“iyi” idi. Dekspantenol i\u00e7in kar\u015f\u0131l\u0131k gelen derecelendirmeler%\n97.4 ve% 92.3 idi. Sonu\u00e7 olarak, hamamelis merhem, 11 ya\u015f\u0131na kadar olan\n\u00e7ocuklarda baz\u0131 cilt bozukluklar\u0131 i\u00e7in etkili ve g\u00fcvenli bir\ntedavidir. G\u00f6zlenen etkiler dekspantenole benzer.<\/p>\n\n\n\n

MAKALE 4-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1177\/1203475416683390<\/a><\/p>\n\n\n\n

Botanicals With Dermatologic Properties Derived From\nFirst Nations Healing: Part 2-Plants and Algae<\/h1>\n\n\n\n

Giri\u015f: <\/strong>Bitkiler\nve algler, hem geleneksel Birinci Uluslar\u0131n iyile\u015fmesinde hem de modern\ndermatolojide cilt ko\u015fullar\u0131n\u0131n tedavisinde merkezi bir rol oynam\u0131\u015ft\u0131r. Bu\n\u00e7al\u0131\u015fman\u0131n amac\u0131 deniz yosunu, cad\u0131 f\u0131nd\u0131\u011f\u0131, bearberry ve mayapple’\u0131n\ndermatolojik kullan\u0131m\u0131n\u0131 destekleyen kan\u0131tlar\u0131 incelemektir.<\/p>\n\n\n\n

Y\u00f6ntemler: <\/strong>Geleneksel\n\u0130lk Uluslar cilt hastal\u0131\u011f\u0131 tedavilerinde kullan\u0131lan d\u00f6rt bitki ve alg uzman\ntavsiyelerine g\u00f6re se\u00e7ilmi\u015ftir. Dil k\u0131s\u0131tlamalar\u0131 olmadan ilgili\nal\u0131nt\u0131lar\u0131 tan\u0131mlamak i\u00e7in \u00e7e\u015fitli veritabanlar\u0131 ara\u015ft\u0131r\u0131ld\u0131.<\/p>\n\n\n\n

Bulgular: <\/strong>Deniz\nyosunu, akne ve k\u0131r\u0131\u015f\u0131kl\u0131klar\u0131n tedavisinde potansiyel klinik kullan\u0131ma\nsahiptir ve biyofonksiyonel tekstillere dahil edilebilir. Cad\u0131 f\u0131nd\u0131\u011f\u0131,\ninflamasyon ve bebek bezi dermatitinin etkili ve iyi tolere edilen bir\ntedavisidir. Bearberry yapraklar\u0131, hiperpigmentasyonun tedavisi i\u00e7in bir\nalternatif olan cilt ayd\u0131nlat\u0131c\u0131 bir madde olan arbutin i\u00e7erir. Mayapple,\nkondiloma accuminata, molluscum contagiosum ve inat\u00e7\u0131 palmoplantar si\u011filler\ni\u00e7in bir tedavi olan podophyllotoxin i\u00e7erir.<\/p>\n\n\n\n

Tart\u0131\u015fma: <\/strong>Yayg\u0131n\nbitkiler ve algler cilt \u00fczerinde faydal\u0131 etkileri olabilecek biyoaktif\nmaddelerle doludur. Daha fazla ara\u015ft\u0131rma, gelecekte yeni ve yenilik\u00e7i\n\u00fcr\u00fcnlere kap\u0131 a\u00e7acakt\u0131r. Bu \u00e7al\u0131\u015fman\u0131n s\u0131n\u0131rlamalar\u0131, \u00e7al\u0131\u015fmam\u0131z\u0131n\nkapsam\u0131n\u0131n, Dermatolojik tedaviler i\u00e7in \u0130lk Milletler taraf\u0131ndan kullan\u0131lan\nbitkilerin geni\u015fli\u011finin k\u00fc\u00e7\u00fck bir \u00f6rne\u011fi olan 4 bitki ve alg ile s\u0131n\u0131rl\u0131\noldu\u011funu i\u00e7erir.<\/p>\n\n\n\n

MAKALE 5-) <\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1055\/s-2006-957868<\/a><\/p>\n\n\n\n

Antiviral and Antiphlogistic Activities of Hamamelis\nVirginiana Bark<\/h1>\n\n\n\n

Hamamelis virginiana kabu\u011fundan\nelde edilen ham bir hidroalkolik \u00f6z\u00fct, daha y\u00fcksek ve daha d\u00fc\u015f\u00fck bir molek\u00fcler\na\u011f\u0131rl\u0131k fraksiyonu elde etmek i\u00e7in 3 kDa’l\u0131k bir kesme limiti ile\nultrafiltrasyona (UF) tabi tutuldu. Fraksiyonlar\u0131n karakterizasyonu,\nSephadex LH-20 \u00fczerinde TLC, HPLC, asidik hidroliz ve kromatografi ile\ndenendi. UF-konsantresinin esas olarak oligomerik ila polimerik\nproantosiyanidinlerden (PA) olu\u015ftu\u011fu g\u00f6sterilmi\u015ftir. Bu fraksiyonun Herpes\nsimpleks vir\u00fcs\u00fc tip 1’e (HSV-1) kar\u015f\u0131 \u00f6nemli antiviral aktivite sergiledi\u011fi\nbulunmu\u015ftur. Ek olarak, UV-konsantresi radikal s\u00fcp\u00fcr\u00fcc\u00fc \u00f6zellikler\nsergiledi, alfa-glukosidaz\u0131n yan\u0131 s\u0131ra insan l\u00f6kosit elastaz\u0131n\u0131 (HLE) inhibe\netti ve faredeki kroton ya\u011f\u0131 kulak \u00f6demi testinde g\u00fc\u00e7l\u00fc antiphistik etkiler\nsergiledi.<\/p>\n\n\n\n

MAKALE 6-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1159\/000017904<\/a><\/p>\n\n\n\n

Anti-inflammatory Effect of Hamamelis Lotion in a\nUVB Erythema Test<\/h1>\n\n\n\n

Arkaplan: <\/strong>Hamamelis\nvirginiana, cilt hastal\u0131klar\u0131n\u0131n geleneksel tedavisinde uzun s\u00fcredir\nkullan\u0131lmas\u0131na ra\u011fmen, anti-enflamatuar etkisinin kapsam\u0131n\u0131 tan\u0131mlayan az\nsay\u0131da kontroll\u00fc klinik \u00e7al\u0131\u015fma bulunmaktad\u0131r.<\/p>\n\n\n\n

Ama\u00e7: <\/strong>pH5\nEucerin art losyonunun% 10 hamamelis distilat, ara\u00e7 ve \u00f6nceki bir sat\u0131\u015f sonras\u0131\nform\u00fclasyonu ile anti-enflamatuar etkinli\u011fi, 30 sa\u011fl\u0131kl\u0131 g\u00f6n\u00fcll\u00fcde, enflamasyon\nmodeli olarak modifiye edilmi\u015f bir UVB eritem testi kullan\u0131larak test\nedilmi\u015ftir.<\/p>\n\n\n\n

Y\u00f6ntemler: <\/strong>Her\ndenekte 1 ila 2 MED aras\u0131nda de\u011fi\u015fen d\u00f6rt UVB dozu de\u011ferlendirildi. Arkadaki\ntest alanlar\u0131 \u0131\u015f\u0131nlamay\u0131 takiben 48 saat boyunca okl\u00fczif olarak tedavi\nedildi. Tedavi edilen alanlardaki eritem derecesini ve \u0131\u015f\u0131nlamadan 7, 24\nve 48 saat sonra i\u015flenmemi\u015f, \u0131\u015f\u0131nlanm\u0131\u015f bir kontrol alan\u0131n\u0131 belirlemek i\u00e7in\nkromametri ve g\u00f6rsel puanlama kullan\u0131ld\u0131.<\/p>\n\n\n\n

Bulgular: <\/strong>Eritem\nsupresyonu, hamamelis tarlalar\u0131nda 48 saatte 7 saate yakla\u015f\u0131k% 20 ila% 27\naras\u0131nda de\u011fi\u015fmektedir. Di\u011fer losyonlarla tedavi edilen alanlarda% 11-15\noran\u0131nda bir bask\u0131lama kaydedildi. Hamameliler ve bu losyonlar aras\u0131nda\n\u00f6nemli farkl\u0131l\u0131klar g\u00f6r\u00fclm\u00fc\u015ft\u00fcr.<\/p>\n\n\n\n

Sonu\u00e7: <\/strong>Bu\nveriler,% 10 hamameli ile art\u00e7\u0131 losyonun anti-enflamatuar etkisi i\u00e7in kan\u0131t\nsa\u011flar ve steroid olmayan antienflamatuar ajanlar\u0131n testi i\u00e7in UVB eritem\ntestinin \u00e7oklu UV dozlar\u0131yla yararl\u0131l\u0131\u011f\u0131n\u0131 destekler.<\/p>\n\n\n\n

MAKALE 7-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1111\/j.2042-7158.1994.tb03795.<\/a><\/p>\n\n\n\n

Anti-inflammatory Activity of Polygonum Bistorta,\nGuaiacum Officinale and Hamamelis Virginiana in Rats<\/h1>\n\n\n\n

Polygonum\nbistorta L. Polygonaceae, Guaiacum officinale L. Zygophyllaceae ve Hamamelis\nvirginiana L. Hamamelidaceae’nin sulu etanolik \u00f6zleri, anti-enflamatuar\naktivite a\u00e7\u0131s\u0131ndan tarand\u0131. Karagenan s\u0131\u00e7an pen\u00e7e \u00f6deminin ind\u00fcksiyonundan\n\u00f6nce verilen (100 ve 200 mg kg-1, po), P. bistorta \u00f6z\u00fctleri hem maksimum \u00f6dem\ntepkisini hem de toplam \u00f6dem tepkisini (zaman kursu e\u011frisinin alt\u0131ndaki alan\nolarak izlenir) \u00f6nemli \u00f6l\u00e7\u00fcde bast\u0131rd\u0131. H. virginiana aktif de\u011fildi ve G.\nofficinale sadece 200 mg kg-1’de aktifti. Adjuvan artrit ind\u00fcksiyonundan\n\u00f6nce uygulanan 200 mg kg-1’de P. bistorta, adjuvan kaynakl\u0131 s\u0131\u00e7an pen\u00e7e\n\u015fi\u015fmesinin hem akut hem de kronik fazlar\u0131n\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde inhibe ederken, G.\nofficinale ve H. virginiana sadece kronik faza kar\u015f\u0131 aktifti. P. ile ilgili\ndi\u011fer \u00e7al\u0131\u015fmalar. bistorta (100-800 mg kg-1), karagenan kaynakl\u0131 s\u0131\u00e7an\npen\u00e7e \u00f6deminin 100-400 mg kg-1 doz aral\u0131\u011f\u0131nda doza ba\u011fl\u0131 bir inhibisyonunu\nortaya \u00e7\u0131karm\u0131\u015ft\u0131r, E50 de\u011feri yakla\u015f\u0131k 158.5 mg kg-1’dir. Enflamatuar\nyan\u0131tlar\u0131n ba\u015flamas\u0131ndan sonra uygulanan ekstrakt (200 mg kg-1), karagenan ve\nadjuvan kaynakl\u0131 s\u0131\u00e7an pen\u00e7e \u015fi\u015fmesinin seyrini tersine \u00e7evirdi. Sonu\u00e7lar,\nP. bistorta, G. officinale ve H. virginiana \u00f6zlerinin antienflamatuar maddeler\ni\u00e7erdi\u011fini do\u011frulamaktad\u0131r.<\/strong><\/p>\n\n\n\n

MAKALE \ud83d\ude0e<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1007\/bf00316465<\/a><\/p>\n\n\n\n

Anti-inflammatory Activity of Hamamelis Distillate\nApplied Topically to the Skin. Influence of Vehicle and Dose<\/h1>\n\n\n\n

Hamamelis kremi (PC’siz) ve papatya\nkremi. \u0130kinci preparat ayr\u0131ca hamamelis PC-kreminden daha az\ng\u00fc\u00e7l\u00fcd\u00fcr. Tabakan\u0131n soyulmas\u0131ndan 4 ila 8 saat sonra eritem hidrokortizon\ntaraf\u0131ndan bast\u0131r\u0131ld\u0131 (P <veya = 0.05). \u0130nflamasyon ayr\u0131ca d\u00fc\u015f\u00fck doz\nhamamelis PC-krem ve papatya kreminin ard\u0131ndan daha az belirgindi. Bununla\nbirlikte, Hamamelis PC-kremi hidrokortizondan daha az etkili\ng\u00f6r\u00fcn\u00fcyordu. Genel olarak, g\u00f6rsel skorlama kromametriye g\u00f6re daha\nayr\u0131mc\u0131yd\u0131. Sonu\u00e7lar, PC i\u00e7eren bir ara\u00e7ta hamamelis distilat\u0131n\u0131n\nanti-enflamatuar aktivitesini g\u00f6stermi\u015ftir. Bununla birlikte, ila\u00e7\nkonsantrasyonunda d\u00f6rt kat bir art\u0131\u015f, aktivitede bir art\u0131\u015f \u00fcretmedi. <\/p>\n\n\n\n

MAKALE 9-)<\/strong><\/p>\n\n\n\n

High Molecular Compounds (Polysaccharides and\nProanthocyanidins) From Hamamelis Virginiana Bark: Influence on Human Skin\nKeratinocyte Proliferation and Differentiation and Influence on Irritated Skin<\/h1>\n\n\n\n

Hamamelis kabu\u011fundan elde edilen\nekstraktlar uzun zamand\u0131r cilt hastal\u0131klar\u0131n\u0131n tedavisinde ve kozmetik\nform\u00fcllerde kullan\u0131lmas\u0131na ra\u011fmen, farkl\u0131 Hamamelis kabu\u011fu bile\u015fenlerinin\naktivitesini do\u011frulayan sadece birka\u00e7 farmakolojik ara\u015ft\u0131rma vard\u0131r. Bu\nnedenle iki ana bile\u015fen s\u0131n\u0131f\u0131, yani polimerik proantosiyanidinler ve\npolisakkaritler Hamamelis kabu\u011fundan izole edildi ve k\u00fclt\u00fcrlenmi\u015f insan\nkeratinositlerinin \u00e7o\u011falmas\u0131 ve farkl\u0131la\u015fmas\u0131 \u00fczerindeki etkileri a\u00e7\u0131s\u0131ndan\ntest edildi. Esas olarak arabans ve arabinogalaktanlardan olu\u015fan\npolisakkarit fraksiyonu insan keratinozitlerini etkilemese de,\nproantosiyanidinler h\u00fccrelerin proliferasyonunu g\u00fc\u00e7l\u00fc bir \u015fekilde artt\u0131r\u0131rken,\nfarkl\u0131la\u015fma \u00f6nemli \u00f6l\u00e7\u00fcde etkilenmedi. SLS tahri\u015f olmu\u015f cilt \u00fczerinde\nyap\u0131lan bir \u00f6n k\u00fcm\u00fclatif in vivo \u00e7al\u0131\u015fmada, proantosiyanidinlerin\n(ProcyanoPlus) transepidermal su kayb\u0131n\u0131 ve eritem olu\u015fumunu azaltt\u0131\u011f\u0131\nkan\u0131tlanm\u0131\u015ft\u0131r. Ayr\u0131ca, klinik bir puanlama prosiyanidinlerin tahri\u015f edici\ns\u00fcre\u00e7leri \u00f6nemli \u00f6l\u00e7\u00fcde etkileyebilece\u011fini g\u00f6stermi\u015ftir.<\/p>\n\n\n\n

MAKALE 10-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1021\/tx700425n<\/a><\/p>\n\n\n\n

Highly Galloylated Tannin Fractions From Witch Hazel\n(Hamamelis Virginiana) Bark: Electron Transfer Capacity, in Vitro Antioxidant\nActivity, and Effects on Skin-Related Cells<\/h1>\n\n\n\n

Cad\u0131 f\u0131nd\u0131\u011f\u0131 (Hammamelis\nvirginiana) kabu\u011fu hem yo\u011funla\u015fm\u0131\u015f hem de hidrolize edilebilir oligomerik\ntanenlerin zengin bir kayna\u011f\u0131d\u0131r. Hem etil asetat hem de suda \u00e7\u00f6z\u00fcn\u00fcr bir\npolifenolik \u00f6z\u00fctten, pirogallol i\u00e7eren polifenoller (proantosiyanidinler,\ngallotanninler ve gallatlar) a\u00e7\u0131s\u0131ndan zengin fraksiyonlar\n\u00fcrettik. Kar\u0131\u015f\u0131mlar, ABTS, DPPH (hidrojen ba\u011f\u0131\u015f\u0131 ve elektron transferi) ve\nHNTTM’ye (elektron transferi) kar\u015f\u0131 serbest radikal temizleyiciler olarak\nolduk\u00e7a aktiftir. Ayr\u0131ca yeni eklenen TNPTM radikalini de azaltabildiler,\nyani baz\u0131 y\u00fcksek derecede reaktif bile\u015fenler i\u00e7erdiler. Cad\u0131 ela\nfenolikleri, k\u0131rm\u0131z\u0131 kan h\u00fccrelerini serbest radikal kaynakl\u0131 hemolizden korudu\nve 3T3 fibroblastlara ve HaCat keratinositlere kar\u015f\u0131 hafif\nsitotoksikti. Ayr\u0131ca, t\u00fcm\u00f6r SK-Mel 28 melanoma h\u00fccrelerinin \u00e7o\u011falmas\u0131n\u0131\n\u00fcz\u00fcm ve \u00e7am prosiyanidinlerden daha d\u00fc\u015f\u00fck konsantrasyonlarda inhibe\nettiler. Pyrogallol k\u0131s\u0131mlar\u0131ndaki y\u00fcksek i\u00e7erik, cad\u0131 ela fenoliklerinin\ncilt h\u00fccreleri \u00fczerindeki etkisinin arkas\u0131nda olabilir. En sitotoksik ve\nantiproliferatif kar\u0131\u015f\u0131mlar da elektron transfer ajanlar\u0131 olarak en verimli\noldu\u011fu i\u00e7in, polifenollerin nihai varsay\u0131lan antioksidan etkisinin k\u0131smen\nredoks yoluyla \u00fcretilen reaktif oksijen t\u00fcrlerinin sa\u011flad\u0131\u011f\u0131 hafif proksidan\nzorluklar\u0131 ile savunma sistemlerinin uyar\u0131lmas\u0131na ba\u011fl\u0131 olabilece\u011fini\nvarsay\u0131yoruz.<\/strong><\/p>\n\n\n\n

MAKALE 11-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1007\/bf00194335<\/a><\/p>\n\n\n\n

Comparative Efficacy of Hamamelis Distillate and\nHydrocortisone Cream in Atopic Eczema<\/h1>\n\n\n\n

Orta derecede \u015fiddetli atopik\negzamas\u0131 olan 72 hastada 14 g\u00fcn s\u00fcren \u00e7ift k\u00f6r, randomize, e\u015fle\u015ftirilmi\u015f bir\n\u00e7al\u0131\u015fmada, hamamelis distilat kremi (0.64 mg keton \/ 100 g ile 5.35 g hamamelis\ndistilat) kar\u015f\u0131l\u0131k gelen ila\u00e7s\u0131z ara\u00e7 ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131 ve% 0.5 hidrokortizon\nkremi ve \u015fiddetli atopik egzama (toplam puanlar\u0131n delta de\u011ferleri), yani\nka\u015f\u0131nt\u0131, eritem ve \u00f6l\u00e7eklendirme gibi temel kriterlerin azalt\u0131lmas\u0131\nde\u011ferlendirildi. Her grupta otuz alt\u0131 hasta tedavi edildi, bu da verum ve\nkontrol aras\u0131nda% 10 fark\u0131n tespit edilmesine izin verdi (do\u011frulay\u0131c\u0131\n\u00e7al\u0131\u015fma). Etkiler Wilcokson testi kullan\u0131larak kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131. Test\nalanlar\u0131n\u0131n temel kriterlerinin ortalama toplam puanlar\u0131 5.3-5.5 idi. T\u00fcm\ntedavi rejimleri 1 hafta sonra ka\u015f\u0131nt\u0131, eritem ve \u00f6l\u00e7eklenmeyi \u00f6nemli \u00f6l\u00e7\u00fcde\nazaltt\u0131. Hidrokortizonun hamamelis dam\u0131t\u0131lmas\u0131ndan daha \u00fcst\u00fcn oldu\u011fu\nkan\u0131tlanm\u0131\u015ft\u0131r. Temel kriter puanlar\u0131 s\u0131ras\u0131yla 2,7 ve 1,6 azald\u0131. Bu\npreparatlar aras\u0131ndaki fark\u0131 g\u00f6stermek i\u00e7in k\u00fc\u00e7\u00fck \u00f6l\u00e7\u00fctlerin delta de\u011ferleri ve\nglobal etkinlik derecesi de kullan\u0131lm\u0131\u015ft\u0131r. Bununla birlikte, Hamamelis\ndistilat kremi ara\u00e7tan farkl\u0131 de\u011fildi. Temel kriterlerin ortalama delta\nde\u011ferleri s\u0131ras\u0131yla 1.8 ve 2.0 idi. T\u00fcm preparatlar iyi tolere\nedildi. Alt\u0131 hastada istenmeyen kutan\u00f6z reaksiyonlar meydana geldi, ancak\nenflamatuar yap\u0131lar\u0131 ve ara\u00e7la tedavi edilen hastalara hapsedilmeleri nedeniyle\nger\u00e7ek olumsuz etkileri de\u011fil, daha ziyade etkinlik eksikli\u011fini temsil\nedebilirler. Sonu\u00e7lar, d\u00fc\u015f\u00fck doz hidrokortizon kreminin hamamelis distilat\nkremine g\u00f6re \u00fcst\u00fcnl\u00fc\u011f\u00fcn\u00fc kan\u0131tlamaktad\u0131r ve bu preparat\u0131 takiben terap\u00f6tik\nsonu\u00e7, baz preparasyonu takip etmekten daha iyi de\u011fildir.<\/strong><\/p>\n\n\n\n

MAKALE 12-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1007\/s10354-016-0536-0<\/a>
\nClinical Trial\nShows Lasting Function of a New Moisturizing Cream Against Vaginal Dryness<\/strong><\/strong><\/p>\n\n\n\n

Vajinal kuruluk ve ili\u015fkili\nsemptomlar herhangi bir ya\u015ftaki kad\u0131nlarda ortaya \u00e7\u0131kabilir ve menopozdan sonra\ns\u0131k g\u00f6r\u00fclen bir y\u00fckt\u00fcr. Kuzey Amerika Menopoz Derne\u011fi, uzun s\u00fcreli\nhormonal olmayan vajinal kremleri birinci basamak tedavi olarak\n\u00f6nermektedir. Bu t\u00fcr yeni bir krem \u200b\u200bgeli\u015ftirildi (Avusturya ve Almanya’da\nRemifemin\u00ae FeuchtCreme). Bu hormon i\u00e7ermeyen krem, hamamelis virginiana\ndam\u0131t\u0131lm\u0131\u015f ve k\u00f6kl\u00fc vajinal krem \u200b\u200bbile\u015fenleri i\u00e7erir. A\u00e7\u0131k bir giri\u015fimsel\nklinik \u00e7al\u0131\u015fmada fiziksel fonksiyonunu ve tolere edilebilirli\u011fini\nara\u015ft\u0131rd\u0131k. 20 postmenopozal kad\u0131n (54-76 ya\u015f, medyan 60) vajinal\nkurulu\u011funu 7 g\u00fcn boyunca g\u00fcnde bir kez bu kremi kullanarak tedavi etti ve\nsemptomlar\u0131n\u0131 daha \u00f6nce, ilk uygulamadan 4 ila 8 saat ve son uygulamadan 14 ila\n22 saat sonra bildirdi. Bir doktor tolere edilebilirli\u011fi ve lokal fiziksel\nfonksiyonu de\u011ferlendirdi. T\u00fcm hastalar \u00e7al\u0131\u015fmay\u0131 tamamlad\u0131. Lokal\nfiziksel fonksiyon, ba\u015flang\u0131\u00e7taki kuruluktan (ortalama 4.0 \u00b1 SD 1.8) normal nem\nseviyesine, ortalama olarak (ilk \u00f6nce 6.3 \u00b1 2.1, son uygulamadan sonra 6.7 \u00b1\n2.1, p = 0.0001) \u00f6nemli \u00f6l\u00e7\u00fcde iyile\u015fti. Vajinal kuruluk hissinin\nsubjektif de\u011ferlendirmesi her iki zaman i\u00e7in de anlaml\u0131 bir iyile\u015fme g\u00f6sterdi\n(p = 0.0001). Nemlendirilmi\u015f ba\u015flang\u0131\u00e7 \u200b\u200bve s\u00fcrenin uygulamadan 0 ila 2\ndakika ve 11.3 \u00b1 6.9 saat oldu\u011fu bildirilmi\u015ftir. T\u00fcm kad\u0131nlar ba\u015flang\u0131\u00e7ta\nvajinal kuruluk bildirmi\u015ftir. Hastalar\u0131n% 55 ve 80’i ilk uygulamadan sonra\nve ara\u015ft\u0131rman\u0131n sonunda kuruluk bildirmemi\u015ftir. Krem, uygulama yerinde 21\nsaate kadar g\u00f6r\u00fcld\u00fc. Tolere edilebilirlik de\u011ferlendirmeleri zaman i\u00e7inde\nherhangi bir ilgili de\u011fi\u015fiklik ortaya koymam\u0131\u015ft\u0131r. D\u00f6rt hastada hepsi ciddi\nolmayan ve hafif \u015fiddette d\u00f6rt advers olay vard\u0131: idrar aciliyeti (2), ilk\nuygulamadan sonra ishal (1) ve hafif lekelenme (1). \u0130kincisine,\naplikat\u00f6r\u00fcn kuru y\u00fczeyi neden olmu\u015ftur ve sonraki uygulamalarda aplikat\u00f6r\u00fcn\ny\u00fczeyini nemlendirerek \u00f6nlenmi\u015ftir. Sonu\u00e7 olarak, bu \u00e7al\u0131\u015fma sonu\u00e7lar\u0131 bu\nyeni vajinal nemlendirici kremin iyi tolere edilen ve uzun etkili bir\nfonksiyonunu g\u00f6stermektedir. Daha fazla hastada daha ileri klinik\nara\u015ft\u0131rmalar yap\u0131lacakt\u0131r.<\/strong><\/p>\n\n\n\n

MAKALE 13-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1002\/1099-1573(200012)14:8%3C612::aid-ptr677%3E3.0.co;2-t<\/a><\/p>\n\n\n\n

Antioxidants in Medicinal Plant Extracts. A Research\nStudy of the Antioxidant Capacity of Crataegus, Hamamelis and Hydrastis<\/h1>\n\n\n\n

Avrupa ve Kuzey Amerika’ya \u00f6zg\u00fc, t\u0131pta kalp ve dola\u015f\u0131m fonksiyonlar\u0131n\u0131n\ntedavisinde kullan\u0131lan Crataegus oxyacantha, Hamamelis virginiana, Hydrastis\ncanadensis \u00f6z\u00fctlerinin antioksidan kapasitesi ara\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r. Bu\n\u00f6z\u00fctlerde bulunan t\u00fcm hidrojen ba\u011f\u0131\u015f\u00e7\u0131 antioksidanlar taraf\u0131ndan verilen toplam\nantioksidan potansiyel, ABTS deneyi ile de\u011ferlendirilmi\u015f ve nispi antioksidan\npotansiyel s\u0131ras\u0131 belirlenmi\u015ftir. Ekstraktlarda bulunan antioksidan u\u00e7ucu\nbile\u015fiklerin kimyasal tan\u0131mlamas\u0131 i\u00e7in k\u00fctle spektrometrisine (GC-MS) ba\u011fl\u0131 gaz\nkromatografisi kullan\u0131lm\u0131\u015ft\u0131r. GC-MS verileri, ABTS deneyi kullan\u0131larak\nelde edilen sonu\u00e7larla ili\u015fkiliydi.<\/h1>\n\n\n\n

MAKALE 14-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1111\/j.1610-0387.2010.07472.x<\/a><\/p>\n\n\n\n

Which Plant for Which Skin Disease? Part 2:\nDermatophytes, Chronic Venous Insufficiency, Photoprotection, Actinic\nKeratoses, Vitiligo, Hair Loss, Cosmetic Indications<\/h1>\n\n\n\n

Bu makale dermatolojide bilimsel\nolarak de\u011ferlendirilen bitki ekstraktlar\u0131n\u0131 incelememize devam\netmektedir. Dermatofitlere kar\u015f\u0131 etkili bitkilerden sonra, kronik ven\u00f6z\nyetmezlikte anti-\u00f6dem etkileri olan bitkiler tart\u0131\u015f\u0131lmaktad\u0131r. \u00dcz\u00fcm asma\nyapraklar\u0131ndan (Vitis vinifera), at kestanesi (Aesculus hippocastanum), deniz\n\u00e7am\u0131 (Pinus maritima) ve kasap s\u00fcp\u00fcrgesinin (Ruscus aculeatus) bitki \u00f6zlerinin\nkronik ven\u00f6z yetmezlikteki \u00f6demi azaltabilece\u011fine dair randomize klinik\n\u00e7al\u0131\u015fmalardan iyi kan\u0131tlar vard\u0131r. Cad\u0131 f\u0131nd\u0131\u011f\u0131 (Hamamelis virginiana),\nye\u015fil \u00e7ay (Camellia sinensis), e\u011freltiotu Polypodium leucotomos ve\ndi\u011ferlerinden bitki \u00f6zleri, topikal veya sistemik olarak uyguland\u0131\u011f\u0131nda cildi\ng\u00fcne\u015f yan\u0131\u011f\u0131ndan ve foto\u011fraflanmadan koruyabilen antioksidan polifenolik\nbile\u015fikler i\u00e7erir. Bah\u00e7e spurjundan (Euphorbia peplus) ve hu\u015f kabu\u011fundan\n(Betula alba) ekstraktlar\u0131n, faz II \u00e7al\u0131\u015fmalar\u0131nda aktinik keratozlar\u0131n\ntedavisinde etkili oldu\u011fu g\u00f6sterilmi\u015ftir. Baz\u0131 bitki \u00f6zleri ayr\u0131ca\nvitiligo, \u00e7e\u015fitli sa\u00e7 d\u00f6k\u00fclmesi ve pigmentasyon bozukluklar\u0131n\u0131n tedavisinde ve\nestetik dermatolojide ara\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r.<\/p>\n\n\n\n

MAKALE 15-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1159\/000064265<\/a><\/p>\n\n\n\n

Antiseptic Effect of a Topical Dermatological\nFormulation That Contains Hamamelis Distillate and Urea<\/h1>\n\n\n\n

Ama\u00e7: <\/strong>Hamamelis\n(Aqua Hamamelidis), ABD Farmakopesi 23 (USP) 23 ve her iki aktif bile\u015feni\ni\u00e7eren topikal dermatolojik bir preparat olarak form\u00fcle edilmi\u015f \u00fcre\ndam\u0131t\u0131lmas\u0131n\u0131n antimikrobiyal aktivitesini belirlemek.<\/p>\n\n\n\n

Y\u00f6ntemler: <\/strong>Basit\nokl\u00fczyon testi ve geni\u015flemi\u015f flora testi ile 15 sa\u011fl\u0131kl\u0131 g\u00f6n\u00fcll\u00fcde in vivo\n\u00e7al\u0131\u015fmalar ger\u00e7ekle\u015ftirdik. Agar dif\u00fczyon testi ile in vitro \u00e7al\u0131\u015fmalar da\nger\u00e7ekle\u015ftirdik.<\/p>\n\n\n\n

Sonu\u00e7lar: <\/strong>Okl\u00fczyon\ntesti ve geni\u015fletilmi\u015f flora testi, Hamamelis distilat (% 90) ve \u00fcre (% 5)\ni\u00e7eren bir \u00fcr\u00fcn i\u00e7in di\u011fer bile\u015fenler aras\u0131nda \u00f6nemli antimikrobiyal aktivite\ng\u00f6sterdi. Geni\u015fletilmi\u015f flora testi, Hamamelis distilat ve \u00fcre i\u00e7in \u00f6nemli\nantimikrobiyal aktivite g\u00f6stermi\u015ftir. Basit okl\u00fczyon testi ayn\u0131 e\u011filimi\ng\u00f6sterdi, ancak sonu\u00e7lar anlaml\u0131 de\u011fildi. Agar dif\u00fczyon testi, di\u011fer\norganizmalar aras\u0131nda Staphylococcus aureus ve Candida albicans’\u0131n\ninhibisyonunu g\u00f6sterdi. Ayn\u0131 y\u00f6ntemi kullanarak klorheksidin diglukonat ve\nfuksinin daha \u00f6nceki \u00e7al\u0131\u015fmalar\u0131yla kar\u015f\u0131la\u015ft\u0131r\u0131lmas\u0131, Hamamelis distilat ve\n\u00fcre antimikrobiyal aktivitelerinin nispeten zay\u0131f oldu\u011funu g\u00f6sterdi. Bu\nbulgu, agar dif\u00fczyon testinde (bitmi\u015f dozaj formunun% 100’\u00fc kullan\u0131larak)\ng\u00f6zlenen zay\u0131f inhibit\u00f6r aktivite ile desteklenmektedir.<\/p>\n\n\n\n

Sonu\u00e7: <\/strong>Hamamelis\ndistilat ve \u00fcre form\u00fclasyonlar\u0131 esas olarak dermatit idame tedavisinde\nantienflamatuar, nemlendirici ve bariyer stabilize edici etkileri i\u00e7in\nkullan\u0131l\u0131r. Bakteriyel kolonizasyon, atopik dermatit ve intertrigo\npatogenezinde merkezi bir role sahip oldu\u011fundan, bu t\u00fcr \u00fcr\u00fcnlerin\nantimikrobiyal aktivitesinin ho\u015f ve ek bir fayda oldu\u011fu d\u00fc\u015f\u00fcn\u00fclmektedir<\/p>\n\n\n\n

MAKALE 15-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1016\/j.pdpdt.2019.05.027<\/a><\/p>\n\n\n\n

The Potential of Commercially Available\nPhytotherapeutic Compounds as New Photosensitizers for Dental Antimicrobial\nPDT: A Photochemical and Photobiological in Vitro Study<\/h1>\n\n\n\n

Bu \u00e7al\u0131\u015fma, ticari olarak temin\nedilebilen Curcuma longa, Citrus lemon, Hamamelis virginiana ve Hypericum\nperforatum \u00f6zlerinin Antimikrobiyal Fotodinamik Terapide (aPDT)\nfotosensitizerler olarak etkinli\u011fini de\u011ferlendirmi\u015ftir. Her bir \u0131\u015f\u0131\u011fa\nduyarl\u0131la\u015ft\u0131r\u0131c\u0131 (PS), ideal \u0131\u015f\u0131k kayna\u011f\u0131n\u0131 belirlemek i\u00e7in 350 ila 750 nm\naras\u0131nda bir spektrofotometrede analiz edildi. Emilim bantlar\u0131\nbelirlendikten sonra \u00fc\u00e7 \u0131\u015f\u0131k kayna\u011f\u0131 se\u00e7ildi. Kullan\u0131m konsantrasyonunu\nbelirlemek i\u00e7in, bile\u015fikler boyama riskini de\u011ferlendirmek i\u00e7in s\u0131\u011f\u0131r dentin\n\u00f6rnekleri \u00fczerinde farkl\u0131 konsantrasyonlarda test\nedilmi\u015ftir. Konsantrasyon belirlendikten sonra PS’ler, fibroblast ve\nbakteri k\u00fclt\u00fcr\u00fcnde koyu toksisite ve fototoksisite a\u00e7\u0131s\u0131ndan\nde\u011ferlendirildi. Her bile\u015fik daha sonra her bir \u0131\u015f\u0131k kayna\u011f\u0131 ile \u0131\u015f\u0131nland\u0131\nve reaktif oksijen t\u00fcrlerinin (ROS) \u00fcretimi i\u00e7in de\u011ferlendirildi.2<\/sup> . Test\nedilen bile\u015fikler, g\u00f6r\u00fcn\u00fcr spektrumun \u00fc\u00e7 band\u0131nda \u0131\u015f\u0131k emilimi sergiledi:\nmenek\u015fe (405 nm), mavi (460 nm) ve k\u0131rm\u0131z\u0131 (660 nm). 1: 6 konsantrasyonda,\nbile\u015fiklerin hi\u00e7biri h\u00fccrelerde veya bakteriyel s\u00fcspansiyonda \u00f6nemli bir\ntoksisite g\u00f6stermedikleri i\u00e7in di\u015f lekelenmesine neden olmam\u0131\u015ft\u0131r. Ek\nolarak, bile\u015fikler her dalga boyunda \u0131\u015f\u0131nland\u0131\u011f\u0131nda \u00f6nemli ROS \u00fcretimi\ng\u00f6zlendi. Plastonik ve biyofilm bakteriler \u00fczerinde aPDT uyguland\u0131\u011f\u0131nda,\nher iki durumda da \u00f6nemli miktarda mikrobiyal azalma g\u00f6zlemlendi ve 5Logs’a\nkadar bir azalma elde edildi. Sonu\u00e7 olarak, Curcuma longa, Citrus lemon,\nHamamelis virginiana ve Hypericum perforatum \u00f6zleri, aPDT’de fotosensitize\nedici ajanlar olarak kullan\u0131m potansiyeli sergilemi\u015ftir.<\/strong><\/p>\n\n\n\n

MAKALE 16-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/https:\/\/doi.org\/10.5005\/jp-dergileri-10024-1739<\/a><\/p>\n\n\n\n

Effectiveness of Oral Antiseptics on Tooth Biofilm:\nA Study in Vivo<\/h1>\n\n\n\n

Ama\u00e7: <\/strong>Plak\nindeksinin \u00f6l\u00e7\u00fcm\u00fc ile be\u015f farkl\u0131 gargara y\u0131kama etkinli\u011finin de\u011ferlendirilmesi.<\/p>\n\n\n\n

Gere\u00e7 ve y\u00f6ntem: <\/strong>A\u011f\u0131z\ny\u0131kama suyunun etken maddesine g\u00f6re be\u015f grubun bloklar\u0131 halinde randomize\nedilen bu k\u00f6r \u00e7al\u0131\u015fmada elli denek yer ald\u0131: CHX grubu (% 0.12 klorheksidin\nglukonat), u\u00e7ucu ya\u011flar (EO) grubu, setilpiridinyum klor\u00fcr (TBM) grubu , Tri\ngrubu (triklosan) ve Hamamelis virginiana (HV) grubu. T\u00fcm denekler 7, 14\nve 21 g\u00fcnde bakteri pla\u011f\u0131 indeksinde bir azalma a\u00e7\u0131s\u0131ndan de\u011ferlendirildi.<\/p>\n\n\n\n

Bulgular: <\/strong>De\u011ferlendirme\ns\u00fcresi boyunca ortalama plak indeksinde anlaml\u0131 bir azalma vard\u0131 (p <0.01)\nve de\u011ferlendirme s\u00fcresi boyunca azalma a\u011f\u0131z gargaralar\u0131 aras\u0131nda farkl\u0131yd\u0131 (p\n<0.01). 21 g\u00fcn\u00fcn sonunda plak endeksindeki azalma, azalan s\u0131rada\nCHX> EO> TBM> Tri> YG idi.<\/p>\n\n\n\n

Sonu\u00e7: <\/strong>De\u011ferlendirme\nd\u00f6neminde plak indeksindeki azalma a\u011f\u0131z y\u0131kama tipleri aras\u0131nda\nfarkl\u0131yd\u0131. Aktif bile\u015fen klorheksidin i\u00e7eren gargara en etkili olan\u0131d\u0131r,\nbunu u\u00e7ucu ya\u011f, setilpiridinyum klor\u00fcr, triklosan ve H. virginiana takip\netmi\u015ftir.<\/p>\n\n\n\n

MAKALE 17-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1002\/14651858.CD006304.pub3<\/a><\/p>\n\n\n\n

Local Cooling for Relieving Pain From Perineal\nTrauma Sustained During Childbirth<\/h1>\n\n\n\n

Arkaplan: <\/strong>Perineal\ntravma do\u011fum s\u0131ras\u0131nda yayg\u0131nd\u0131r ve a\u011fr\u0131l\u0131 olabilir. \u00c7a\u011fda\u015f annelik\nuygulamas\u0131, kad\u0131nlara so\u011futma tedavilerinin yerel uygulamas\u0131 da dahil olmak\n\u00fczere bir\u00e7ok a\u011fr\u0131 kesici form sunmay\u0131 i\u00e7erir.<\/p>\n\n\n\n

Ama\u00e7: <\/strong>Lokalize\nso\u011futma tedavilerinin hi\u00e7bir tedavi, di\u011fer so\u011futma tedavisi formlar\u0131 ve so\u011futma\nd\u0131\u015f\u0131 tedavilerle kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda etkinli\u011fini ve yan etkilerini\nde\u011ferlendirmek.<\/p>\n\n\n\n

Arama y\u00f6ntemleri: <\/strong>Cochrane\nGebelik ve Do\u011fum Grubu Deneme Kay\u0131tlar\u0131n\u0131 (10 Ocak 2012), CINAHL (1982-10 Ocak\n2012), Avustralya Yeni Zelanda Klinik Ara\u015ft\u0131rma Kay\u0131tlar\u0131n\u0131 (10 Ocak 2012)\nara\u015ft\u0131rd\u0131k ve bu alandaki uzmanlarla temasa ge\u00e7tik.<\/p>\n\n\n\n

Se\u00e7im kriterleri: <\/strong>Do\u011fum\ns\u0131ras\u0131nda s\u00fcrd\u00fcr\u00fclen perineal travmaya ba\u011fl\u0131 a\u011fr\u0131y\u0131 hafifletmek i\u00e7in hi\u00e7bir\ntedavi veya ba\u015fka tedavilerle perine uygulanan lokal so\u011futma tedavisini\nkar\u015f\u0131la\u015ft\u0131ran yay\u0131nlanm\u0131\u015f ve yay\u0131nlanmam\u0131\u015f randomize ve yar\u0131 randomize\n\u00e7al\u0131\u015fmalar (RCT’ler)<\/p>\n\n\n\n

Yazarlar\u0131n sonu\u00e7lar\u0131: <\/strong>A\u011fr\u0131y\u0131 hafifletmek i\u00e7in do\u011fumdan sonra perine uygulanan lokal\nso\u011futma tedavilerinin (buz paketleri, so\u011fuk jel pedleri, so\u011fuk \/ buzlu\nbanyolar) etkinli\u011fini destekleyen sadece s\u0131n\u0131rl\u0131 kan\u0131t vard\u0131r.<\/strong><\/p>\n\n\n\n

MAKALE 18-)<\/strong><\/p>\n\n\n\n

\nhttps:\/\/scihub.bban.top\/10.1097\/00004770-200403000-00013\n<\/div><\/figure>\n\n\n\n

Accidental Sodium Hypochlorite-Induced Skin Injury\nDuring Endodontic Treatment<\/h1>\n\n\n\n

K\u00f6k kanal\u0131 haz\u0131rl\u0131\u011f\u0131 s\u0131ras\u0131nda\nsodyum hipoklorit \u00e7\u00f6zeltisinin kau\u00e7uk barajdan s\u0131zmas\u0131na ba\u011fl\u0131 kazara cilt\nhasar\u0131 vakas\u0131 bildirilmi\u015ftir. Bir lastik baraj yerle\u015ftirildikten ve k\u00f6k\nkanal tedavisine ba\u015fland\u0131ktan sonra, hasta sodyum hipoklorit irrigasyonu ile\nyanma hissinden \u015fikayet etti. \u015eikayetler uygulay\u0131c\u0131 taraf\u0131ndan g\u00f6z ard\u0131\nedildi ve hastan\u0131n \u00e7enesi \u00fczerinde ve \u00e7evresinde deri d\u00f6k\u00fcnt\u00fcs\u00fc geli\u015fti ve\nard\u0131ndan kabuk olu\u015fumu oldu. Hasta tam iyile\u015fme ile topikal Hamamelis\nvirginiana \u00f6z\u00fct\u00fc ile 2 hafta boyunca t\u0131bbi tedaviye ihtiya\u00e7 duydu.<\/strong><\/p>\n\n\n\n

MAKALE 19-)<\/strong><\/p>\n\n\n\n

\nhttps:\/\/scihub.bban.top\/10.1002\/ptr.904\n<\/div><\/figure>\n\n\n\n

Peroxynitrite Scavenging Activity of Herb Extracts<\/h1>\n\n\n\n

Peroksinitrit (ONOO (-)),\ns\u00fclf\u00fcridler, lipitler, amino asitler ve n\u00fckleotitler dahil olmak \u00fczere \u00e7e\u015fitli\nh\u00fccresel bile\u015fenlere kar\u015f\u0131 g\u00fc\u00e7l\u00fc oksitleyici \u00f6zelliklere sahip bir\nsitotoksikand\u0131r ve h\u00fccre \u00f6l\u00fcm\u00fcne, lipit peroksidasyonuna, karsinogeneze ve ya\u015flanmaya\nneden olabilir. Bu \u00e7al\u0131\u015fman\u0131n amac\u0131, bitkilerden ONOO (-) atma\nbile\u015fenlerini karakterize etmektir. Yirmi sekiz bitki, bir florometrik\ny\u00f6ntem kullan\u0131larak ONOO (-) temizleme faaliyetleri i\u00e7in tarand\u0131. Otantik\nONOO (-) ilavesinden sonra temizleme etkinli\u011finin g\u00fcc\u00fc a\u015fa\u011f\u0131daki s\u0131radayd\u0131:\ncad\u0131 f\u0131nd\u0131\u011f\u0131 kabu\u011fu> biberiye> yasemin \u00e7ay\u0131> ada\u00e7ay\u0131> kaygan\nkaraa\u011fa\u00e7> siyah ceviz yapra\u011f\u0131> Krali\u00e7e Anne’in dantel> Ihlamur\n\u00e7i\u00e7e\u011fi. Ekstraktlar doza ba\u011fl\u0131 ONOO (-) temizleme aktiviteleri sergiledi. Cad\u0131\nf\u0131nd\u0131\u011f\u0131n\u0131 bulduk (Hamamelis virginiana L. ) kabu\u011fu 28 bitkinin ONOO (-)\natmak i\u00e7in en g\u00fc\u00e7l\u00fc etkiyi g\u00f6sterdi. Cad\u0131 f\u0131nd\u0131\u011f\u0131 kabu\u011funun ana aktif\nbile\u015feni olan Hamamelitannin’in, ONOO (-) ‘yu temizleyebilme yetene\u011fi\ng\u00fc\u00e7l\u00fcd\u00fcr. Hamamelitaninin, ONOO (-) ile ilgili hastal\u0131klar\u0131n \u00f6nlenmesi\ni\u00e7in etkili bir peroksinitrit temizleyici olarak geli\u015ftirilebilece\u011fi\n\u00f6nerilmektedir.<\/p>\n\n\n\n

MAKALE\n20-) <\/h1>\n\n\n\n
\nhttps:\/\/scihub.bban.top\/10.1002\/ptr.1188\n<\/div><\/figure>\n\n\n\n

Antibacterial Activity of Medicinal Plant Extracts\nAgainst Periodontopathic Bacteria<\/h1>\n\n\n\n

Bu \u00e7al\u0131\u015fma Althaea officinalis L.\nk\u00f6klerinin, Arnica montana L. \u00e7i\u00e7ekleri, Calendula officinalis L. \u00e7i\u00e7ekleri,\nHamamelis virginiana L. yapraklar\u0131, Illicium verum Hook’un antibakteriyel\naktivitesini de\u011ferlendirmek i\u00e7in yap\u0131ld\u0131. meyveler ve Melissa officinalis\nL. yapraklar\u0131, anaerobik ve fak\u00fcltatif aerobik periodontal bakterilere kar\u015f\u0131:\nPorphyromonas gingivalis, Prevotella spp., Fusobacterium nucleatum,\nCapnocytophaga gingivalis, Veilonella parvula, Eikenella corrodens,\nPeptostreptococcus microstotiosintoztistiyotintikt. H. virginiana ve A.\nmontana’n\u0131n metanol ekstraktlar\u0131n\u0131n ve daha az bir \u00f6l\u00e7\u00fcde A. officinalis’in\ntest edilen bir\u00e7ok t\u00fcre kar\u015f\u0131 \u00f6nleyici bir aktiviteye (MIC <veya = 2048 mg \/\nL) sahip oldu\u011fu g\u00f6sterilmi\u015ftir. Buna kar\u015f\u0131l\u0131k, M. officinalis ve C.\nofficinalis \u00f6zleri daha d\u00fc\u015f\u00fck bir inhibe edici aktiviteye sahipti\n(MIC> veya = 2048 mg \/ L) Prevotella sp. Illicium verum metanol\n\u00f6z\u00fc, E. corrodens’e kar\u015f\u0131 \u00f6zellikle iyi bir aktiviteye sahip olmas\u0131na ra\u011fmen\n\u00e7ok aktif de\u011fildi. Sonu\u00e7lar periodontal profilaktiklerde topikal ila\u00e7lar\ni\u00e7in H. virginiana, A. montana ve A. officinalis’in alkol ekstraktlar\u0131n\u0131n\nkullan\u0131lmas\u0131n\u0131 \u00f6nermektedir.<\/p>\n\n\n\n

MAKALE 21-)<\/strong><\/p>\n\n\n\n

https:\/\/scihub.bban.top\/10.1016\/S0944-7113(11)80036-X<\/a><\/p>\n\n\n\n

Evidence for the Efficacy and Safety of Topical\nHerbal Drugs in Dermatology: Part I: Anti-inflammatory Agents<\/h1>\n\n\n\n

Topikal bitkisel ila\u00e7lar y\u00fczy\u0131llard\u0131r cilt rahats\u0131zl\u0131klar\u0131n\u0131n tedavisinde\nkullan\u0131lmaktad\u0131r. Halen hastalar taraf\u0131ndan geni\u015f \u00e7apta kabul g\u00f6rseler de,\n\u00f6zellikle dermatologlar aras\u0131ndaki bilimsel sayg\u0131lar\u0131 s\u0131n\u0131rl\u0131d\u0131r. Topikal\nuygulama i\u00e7in \u00e7e\u015fitli bitkisel ila\u00e7lar, yayg\u0131n kullan\u0131mlar\u0131 veya fayda \/ risk\noranlar\u0131na g\u00f6re hala k\u00f6t\u00fc tan\u0131mlanm\u0131\u015f potansiyelleri ile ilgili d\u00fc\u015f\u00fcnmeyi hak\netmektedir. Klinik olarak, papatya (Chamomilla recutita) ve hamamelis\npreparatlar\u0131 \u00f6zellikle iyi belgelenmi\u015ftir. Atopik dermatit gibi yayg\u0131n\ndermatozlarda nihai etkinlik kan\u0131t\u0131 hala eksik olsa da, normal g\u00f6n\u00fcll\u00fclerle yap\u0131lan\ndeneylerden \u00e7\u0131kar\u0131labilece\u011fi gibi, erkeklerde kutan\u00f6z inflamasyona kar\u015f\u0131\naktiviteleri i\u00e7in olduk\u00e7a geni\u015f bir kan\u0131t vard\u0131r. Hamamelis virginiana ile\nbu, \u00f6zellikle umut verici g\u00f6r\u00fcn\u00fcyor, ila\u00e7la ilgili istenmeyen etkiler\nneredeyse yoktur. Papatya preparatlar\u0131nda, g\u00fcvenlik derecesi b\u00fcy\u00fck \u00f6l\u00e7\u00fcde\nkullan\u0131lan bitkiye ba\u011fl\u0131d\u0131r. <\/h1>\n\n\n\n

MAKALE 22-)<\/h1>\n\n\n\n

https:\/\/scihub.bban.top\/10.1111\/j.1600-0536.2007.01250.x<\/a><\/h1>\n\n\n\n

Cosmetics and Herbal Remedies With Compositae Plant Extracts\n– Are They Tolerated by Compositae-allergic Patients?<\/h1>\n\n\n\n

Ama\u00e7: <\/strong>Compositae\nduyarl\u0131 hastalar, Compositae i\u00e7eren kozmetiklerin ve bitkisel ila\u00e7lar\u0131n topikal\nkullan\u0131m\u0131na kar\u015f\u0131 rutin olarak uyar\u0131l\u0131r. Bununla birlikte,\nhassasla\u015ft\u0131r\u0131lm\u0131\u015f ki\u015filerde dermatitin ortaya \u00e7\u0131kma riski bilinmemektedir.<\/p>\n\n\n\n

Ama\u00e7: <\/strong>Bu\n\u00e7al\u0131\u015fman\u0131n temel amac\u0131, arnika (Arnica montana) ve Alman papatyas\u0131na\n(Chamomilla recutita) \u00f6zel at\u0131fta bulunan Compositae alerjik hastalarda\nCompositae t\u00fcrevi kozmetikler ve bitkisel ila\u00e7lar yoluyla do\u011frudan bitki\nalerjeni temas\u0131n\u0131n \u00f6nemini de\u011ferlendirmekti.<\/p>\n\n\n\n

Y\u00f6ntemler: <\/strong>Papatyaya\nduyarl\u0131 12 hastadan 8’i \u00e7ay, krem, merhem ve ya\u011f gibi papatya i\u00e7eren\npreparatlara pozitif test edildi. Arnikaya duyarl\u0131 6 ki\u015fiden 5’i arnika\nbazl\u0131 \u00fcr\u00fcnlere pozitif test edildi.<\/p>\n\n\n\n

Bulgular: <\/strong>Grup\nkozmetik ve \/ veya bitkisel \u00fcr\u00fcn bile\u015fenleri ile yama testi yap\u0131ld\u0131\u011f\u0131nda, bitki\nalerjenleri en s\u0131k pozitif reaksiyonlar ortaya \u00e7\u0131kard\u0131, ancak kokular,\nem\u00fclgat\u00f6rler ve koruyucular da pozitif test edildi. Bitki alerjenleri esas\nolarak Compositae’den t\u00fcretilmi\u015ftir, ancak avokado ya\u011f\u0131 ve Hamamelis virginiana\ntent\u00fcr\u00fc beklenmedik bir \u015fekilde duyarl\u0131la\u015ft\u0131r\u0131c\u0131lar olarak tespit\nedilmi\u015ftir. Kimyasal analizler, Compositae alerjenlerinin hem seskiterpen\nlaktonlar hem de di\u011fer do\u011fal olarak olu\u015fan bile\u015fikler oldu\u011funu g\u00f6sterdi.<\/p>\n\n\n\n

Sonu\u00e7: <\/strong>Compositae-alerjik\nki\u015filer, sadece bitki alerjenleri nedeniyle de\u011fil, ayn\u0131 zamanda \u00e7oklu temas\nalerjisi olan hasta grubunda reaksiyonlara neden olabilecek alerjenik krem\n\u200b\u200bbile\u015fenleri nedeniyle, Compositae i\u00e7eren \u00fcr\u00fcnlerin topikal kullan\u0131m\u0131na kar\u015f\u0131\nuyar\u0131lmal\u0131d\u0131r.<\/p>\n\n\n\n

MAKALE 23-)<\/h1>\n\n\n\n

PMID: 19442393<\/p>\n\n\n\n

Clinical Inquiries. Do Nonmedicated Topicals Relieve\nChildhood Eczema?<\/h1>\n\n\n\n

Yumu\u015fat\u0131c\u0131lar, egzama semptomlar\u0131n\u0131 azaltmak ve \u00e7ocuklarda steroid\nkullanma ihtiyac\u0131n\u0131 azaltmak i\u00e7in etkili birinci basamak tedavidir. Katran\npreparatlar\u0131 i\u015fe yarar, ancak uyum s\u0131n\u0131rl\u0131 olabilir. Gamma-linoleik asit\npreparatlar\u0131, hodan ya\u011f\u0131 ve \u00e7uha \u00e7i\u00e7e\u011fi ya\u011f\u0131 k\u00fc\u00e7\u00fck \u00e7al\u0131\u015fmalarda etkinlik\ng\u00f6sterir. MAS063DP krem \u200b\u200b(Atopiclair) etkilidir. Papatya ve asidik\nkapl\u0131ca suyunda banyo yapmak etkili olabilir, ancak bu tedaviler yeterince\nde\u011ferlendirilmemi\u015ftir. Islak sarg\u0131lar etkili olabilir ancak cilt\nenfeksiyonu riskini art\u0131r\u0131r. Hamamelis dam\u0131t\u0131lm\u0131\u015f kremler ve u\u00e7ucu ya\u011flar\n\/ aromaterapi ile masaj etkisizdir.<\/h1>\n","protected":false},"excerpt":{"rendered":"

A\u015fa\u011f\u0131da cad\u0131 f\u0131nd\u0131\u011f\u0131 bitkisi ile ilgili literat\u00fcre kay\u0131tl\u0131 \u00e7al\u0131\u015fmalar\u0131n \u00f6zeti yer almaktad\u0131r. Bu \u00e7al\u0131\u015fmalar\u0131n tamam\u0131n\u0131 okumak i\u00e7in DOI numalar\u0131ndan ula\u015fabilirsiniz. MAKALE 1-)https:\/\/scihub.bban.top\/10.4103\/0974-7753.139079 North American Virginian Witch Hazel (Hamamelis Virginiana): Based Scalp Care and Protection for Sensitive Scalp, Red Scalp, and Scalp Burn-Out Ama\u00e7: Hassas bir kafa derisi g\u00fcnl\u00fck klinik uygulamada s\u0131k g\u00f6r\u00fclen bir sorundur ve genellikle […]<\/p>\n","protected":false},"author":1,"featured_media":216,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-212","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-literatur"],"yoast_head":"\nCADI FINDI\u011eI(HAMAMEL\u0130S V\u0130RG\u0130N\u0130ANA) - Dr. \u00d6zberk Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.drozberk.com\/index.php\/2020\/05\/15\/cadi-findigihamamelis-virginiana\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CADI FINDI\u011eI(HAMAMEL\u0130S V\u0130RG\u0130N\u0130ANA) - Dr. \u00d6zberk Blog\" \/>\n<meta property=\"og:description\" content=\"A\u015fa\u011f\u0131da cad\u0131 f\u0131nd\u0131\u011f\u0131 bitkisi ile ilgili literat\u00fcre kay\u0131tl\u0131 \u00e7al\u0131\u015fmalar\u0131n \u00f6zeti yer almaktad\u0131r. 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